diff --git a/CHANGELOG.md b/CHANGELOG.md
index a53df5cf..8f9bc6b4 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -32,7 +32,7 @@ and this project adheres to [Semantic Versioning](https://semver.org).
 
 - Xls Reader resolving absolute named ranges to relative ranges [Issue #2826](https://github.com/PHPOffice/PhpSpreadsheet/issues/2826) [PR #2827](https://github.com/PHPOffice/PhpSpreadsheet/pull/2827)
 - Null value handling in the Excel Math/Trig PRODUCT() function [Issue #2833](https://github.com/PHPOffice/PhpSpreadsheet/issues/2833) [PR #2834](https://github.com/PHPOffice/PhpSpreadsheet/pull/2834)
-
+- Invalid Print Area defined in Xlsx corrupts internal storage of print area [Issue #2848](https://github.com/PHPOffice/PhpSpreadsheet/issues/2848) [PR #2849](https://github.com/PHPOffice/PhpSpreadsheet/pull/2849)
 
 ## 1.23.0 - 2022-04-24
 
diff --git a/src/PhpSpreadsheet/Reader/Xlsx.php b/src/PhpSpreadsheet/Reader/Xlsx.php
index ecae5ad7..8eadb39c 100644
--- a/src/PhpSpreadsheet/Reader/Xlsx.php
+++ b/src/PhpSpreadsheet/Reader/Xlsx.php
@@ -1530,13 +1530,18 @@ class Xlsx extends BaseReader
                                                 $rangeSets = preg_split("/('?(?:.*?)'?(?:![A-Z0-9]+:[A-Z0-9]+)),?/", $extractedRange, -1, PREG_SPLIT_NO_EMPTY | PREG_SPLIT_DELIM_CAPTURE);
                                                 $newRangeSets = [];
                                                 foreach ($rangeSets as $rangeSet) {
-                                                    [$sheetName, $rangeSet] = Worksheet::extractSheetTitle($rangeSet, true);
+                                                    [, $rangeSet] = Worksheet::extractSheetTitle($rangeSet, true);
+                                                    if (empty($rangeSet)) {
+                                                        continue;
+                                                    }
                                                     if (strpos($rangeSet, ':') === false) {
                                                         $rangeSet = $rangeSet . ':' . $rangeSet;
                                                     }
                                                     $newRangeSets[] = str_replace('$', '', $rangeSet);
                                                 }
-                                                $docSheet->getPageSetup()->setPrintArea(implode(',', $newRangeSets));
+                                                if (count($newRangeSets) > 0) {
+                                                    $docSheet->getPageSetup()->setPrintArea(implode(',', $newRangeSets));
+                                                }
 
                                                 break;
                                             default: